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The match is scheduled for Tuesday, September 17, 2024, at Old Trafford with a kick-off time of 20:00 BST.
This game marks Barnsley's first trip to Old Trafford since 1998. Barnsley qualified for this round after defeating Sheffield United 1-0 in the second round.
Meanwhile, Manchester United, a historically dominant side, has won 22 out of the 38 previous encounters with Barnsley.
This clash is gaining attention due to Manchester United's recent performances and the expectation of a competitive match in this knockout competition.
Fans are also excited to see key players return to action as United continues to juggle multiple tournaments.
